Think of SS-31 as your mitochondria’s personal bodyguard—a specialized tetrapeptide engineered to penetrate deep into your cellular power plants and protect them from the inside out. Just as a skilled security guard positions themselves at the most vulnerable entry points, SS-31 targets cardiolipin, a critical phospholipid in the inner mitochondrial membrane, stabilizing the very architecture that keeps your cells producing energy efficiently.
Also known as Elamipretide or Bendavia, SS-31 represents one of the most exciting advances in mitochondrial-targeted therapeutics. This compact four-amino-acid peptide (D-Arg-Dmt-Lys-Phe-NHâ‚‚) has captured the attention of researchers worldwide for its remarkable ability to cross mitochondrial membranes and concentrate precisely where oxidative damage occurs most. Unlike broad-spectrum antioxidants that work throughout the cell, SS-31 acts with surgical precision at the mitochondrial level.
What makes SS-31 particularly fascinating is its mechanism—it doesn’t just neutralize free radicals like conventional antioxidants. Instead, it stabilizes the electron transport chain itself, reducing the production of reactive oxygen species at their source while simultaneously enhancing ATP production. This dual action of protection and performance enhancement has made it a compelling subject of research in cardiovascular disease, aging, kidney protection, and neurodegenerative conditions.
