Semax

Semax

Price range: $45.00 through $65.00

Semax is a synthetic peptide that works like a brain booster in research settings, potentially enhancing cognitive function and protecting nerve cells. Originally developed from a natural hormone fragment (ACTH), this peptide has shown promise in studies for improving memory, focus, and even aiding in stroke recovery. Research indicates it may work by increasing important brain growth factors and improving blood flow to the brain.

This lyophilized powder requires reconstitution before use and is intended exclusively for laboratory research purposes, not for human or animal consumption.

Overview

Think of Semax as a molecular key that unlocks your brain’s potential filing cabinet. Just as a skilled librarian can reorganize and optimize a library’s collection, Semax appears to help brain cells communicate more efficiently and protect themselves from damage. This synthetic peptide, derived from a fragment of the natural hormone ACTH, has captured researchers’ attention for its unique ability to potentially enhance cognitive function without the harsh side effects often seen with traditional stimulants.

What makes Semax particularly fascinating to researchers is its gentle yet multifaceted approach to brain support. Unlike caffeine that simply speeds things up, Semax seems to work by nurturing the brain’s natural growth and repair mechanisms, making it a subject of intense study for various neurological applications.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C38H54N12O9

Molar Mass: 826.92 g/mol

CAS: 80714-61-0

Sequence: Met-Glu-His-Phe-Pro-Gly-Pro

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Requires refrigeration after reconstitution

Stability: Stable in lyophilized form

How It Works

Semax operates through several fascinating mechanisms that researchers are still working to fully understand. At its core, it appears to boost the production of two critical brain proteins: brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). Think of these as fertilizer for your brain cells – they help neurons grow, survive, and form new connections.

Primary Mechanisms

Neurotrophin Enhancement

Boosts BDNF and NGF production, promoting neuronal growth, survival, and new connection formation

Neurotransmitter Modulation

Enhances brain communication by modulating serotonin and dopamine systems, upgrading neural network efficiency

Supporting Effects

Antioxidant Properties

Helps clean up harmful molecules that can damage brain cells, providing neuroprotection

Cerebral Blood Flow

Improves blood flow to ensure neurons receive adequate oxygen and nutrients

Research Findings

Laboratory studies have revealed multiple promising applications for Semax across various neurological research areas:

Cognitive Enhancement

Studies have shown that Semax may improve various aspects of cognitive function, including memory formation, attention span, and mental clarity. Researchers have observed enhanced learning capabilities and improved information processing in laboratory settings.

Neuroprotection

Research indicates Semax may protect brain cells from various forms of damage. It appears to reduce the accumulation of beta-amyloid peptides (associated with Alzheimer’s disease) and shield neurons from oxidative stress. This protective effect has made it a subject of interest for neurodegenerative disease research.

Mood Regulation

Through its effects on serotonin and dopamine systems, Semax has shown potential in research for mood stabilization and stress response. Studies suggest it may help regulate emotional responses without the sedating effects of traditional mood medications.

Stroke Recovery

Perhaps one of the most promising areas of research involves Semax’s potential in stroke recovery. Studies have indicated it may help reduce brain damage following stroke and support the recovery of lost functions by promoting neural plasticity and repair mechanisms.

Anti-inflammatory Effects

Research has revealed that Semax possesses anti-inflammatory properties in the brain, potentially reducing neuroinflammation that contributes to various neurological conditions.

Potential Side Effects in Research

While Semax is generally well-tolerated in research settings, some observed effects include:

Neurological

Mild headaches

Vestibular

Temporary dizziness

Immune Response

Potential allergic reactions in sensitive subjects

Local Effects

Nasal irritation (when administered intranasally in studies)

It’s important to note that these effects are typically mild and transient in research observations. However, comprehensive long-term safety data is still being collected.

IMPORTANT: This product is exclusively for laboratory research and not for human or animal use.

References

  1. Grieco SF, et al. “Semax affects copper-induced Aβ aggregation and amyloid formation.” ACS Chem Neurosci. 2022.
  2. Dergunova LV, et al. “Novel insights into protective properties of Semax at transcriptome level.” Genes. 2020.
  3. Samotaeva IS, et al. “Functional connectivity changes from Semax and Selank administration.” Dokl Biol Sci. 2020.
  4. Medvedeva EV, et al. “Semax affects immune and vascular gene expression in focal ischemia.” BMC Genomics. 2014.
  5. Kolomin T, et al. “Semax action on AMPA receptor currents in Purkinje cells.” Bull Exp Biol Med. 2015.
  6. Effects of Semax on global brain ischemia
  7. Semax and its Pro-Gly-Pro fragment in brain plasticity
  8. The heptapeptide Semax stimulates BDNF expression
  9. Antioxidant and antiamnesic effects of Semax
  10. Clinical evaluation of Semax in treatment of neurological diseases
  11. Mendez-David I, et al. “Neurotrophin-based therapeutics for brain disorders: BDNF modulation strategies.” Expert Opin Drug Discov. 2024.

Third-Party Lab Tested

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