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PT-141

PT-141

Original price was: $70.00.Current price is: $50.00.

Research suggests PT-141 works through the brain rather than the bloodstream to influence sexual arousal and desire. Studies show this peptide activates specific receptors in the central nervous system that trigger dopamine release. This unique pathway makes it valuable for researchers studying libido and arousal mechanisms. Unlike compounds that target blood flow, PT-141 directly engages neural pathways involved in motivation and pleasure.

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Overview

PT-141 represents a paradigm shift in sexual dysfunction research. While most compounds in this field work by improving blood flow, PT-141 takes a completely different approach – it works through the brain. By activating specific melanocortin receptors in the central nervous system, this peptide influences sexual arousal at its source, making it a valuable tool for researchers studying the neurological aspects of sexual desire and response.

What makes PT-141 particularly fascinating for researchers is its unique mechanism: it’s like having a backstage pass to the brain’s arousal control room. Rather than simply improving vascular function, PT-141 activates the neural circuits that control sexual desire, offering insights into the software rather than the hardware of sexual function.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C50H68N14O10

Weight: 1025.2 g/mol

CAS: 189691-06-3

Also Known As: Bremelanotide

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Readily dissolves in water

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

Reconstitution: Mix with bacteriostatic water

How It Works

PT-141’s mechanism is fascinatingly different from other compounds in its research category, working through neural pathways rather than vascular mechanisms.

Primary Mechanisms

Melanocortin Receptor Activation

Primarily targets MC4R and MC1R receptors in the brain, activating central arousal pathways.

Central Nervous System Action

Works through neural pathways rather than vascular mechanisms, targeting the brain’s arousal control centers.

Neural Effects

Dopamine Modulation

May increase dopamine release in brain regions associated with sexual arousal and motivation.

Neurotransmitter Influence

Affects various neurotransmitter systems involved in desire and arousal, creating complex neural responses.

Research Findings

Studies on PT-141 have revealed important insights across multiple research domains, from sexual dysfunction to broader neurological applications.

Female Sexual Dysfunction Research

PT-141 has shown significant promise in addressing Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women through central mechanisms.

Increased sexual desire independent of hormonal status
Improved sexual arousal and satisfaction scores
Effects work through central mechanisms
Consistent results across diverse study populations

Male Sexual Function Studies

While initially developed for female sexual dysfunction, research in males has demonstrated unique central nervous system benefits.

Potential benefits for erectile function through central mechanisms
Applications where vascular treatments are ineffective
Effects on psychological aspects of sexual dysfunction
Results independent of testosterone levels

Neurological Research Applications

Beyond sexual function, PT-141 provides valuable insights into fundamental brain mechanisms and neural pathway regulation.

Melanocortin system function in the brain
Neural pathways controlling motivation and reward
Central nervous system regulation of physiological responses
Brain-body connections in arousal and desire

Additional Research Areas

Emerging studies explore broader applications of PT-141 across multiple physiological and behavioral research domains.

Dermatological Effects: Potential applications in pigmentation disorders
Cardiovascular Function: Effects on blood pressure and heart rate
Metabolic Research: Possible influences on energy metabolism
Mood and Behavior: Impact on general motivation and well-being

Potential Side Effects in Research

Researchers should monitor for these commonly observed effects during PT-141 studies.

Gastrointestinal

Nausea is the most frequently reported effect in research studies, typically mild to moderate in severity.

Vascular

Facial flushing and warmth, along with mild blood pressure changes in some research cases.

Neurological

Headaches in some subjects, typically mild and resolving after discontinuation.

Dermatological

Focal hyperpigmentation (darkening of skin patches), typically reversible in research settings.

Cardiovascular

Mild blood pressure changes and heart rate variations observed in some research cases.

Most effects are mild to moderate and resolve after discontinuation in research settings. Individual responses may vary significantly.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

References

  1. Kingsberg SA, et al. “Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder.” Obstet Gynecol. 2019.
  2. Clayton AH, et al. “Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women.” Womens Health. 2016.
  3. Diamond LE, et al. “An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141).” J Sex Med. 2006.
  4. Kingsberg SA, Clayton AH, et al. “Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.” Obstet Gynecol. 2019.
  5. Simon JA, et al. “Safety Profile of Bremelanotide Across the Clinical Development Program.” Pharmaceuticals. 2022.
  6. Pfaus JG, et al. “The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women.” CNS Spectr. 2021.
  7. Althof SE, et al. “Understanding Female Sexual Dysfunction and Treatment Options.” J Sex Med. 2017.
  8. Goldstein I, et al. “An evaluation of bremelanotide injection for the treatment of hypoactive sexual desire disorder.” Expert Opin Pharmacother. 2023.
✓ THIRD-PARTY LAB TESTED

Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.952%
Purity
16HBE
Batch
August 2025
Date
View Certificate →
Weight0.08 lbs
Dimensions0.87 × 1.18 × 0.87 in
Size

10mg

SKU: OATH-PT-141 Category: Tag:
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