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MOTS-c

MOTS-c

Price range: $60.00 through $190.00

Research suggests MOTS-c may help cells produce energy more efficiently and support healthy metabolism. Studies show this mitochondrial peptide could improve how the body uses sugar, reduce inflammation, and support healthy aging. Scientists are especially excited about its potential to enhance exercise performance and protect heart health. This lyophilized powder requires reconstitution with bacteriostatic water before use.

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✓ THIRD-PARTY LAB TESTED

Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.547%
Purity
47CBF
Batch
January 2026
Date
View Certificate →

Overview

Think of MOTS-c as your cells’ energy management consultant-a specialized peptide that emerges from the mitochondria (your cellular power plants) to help optimize how your body uses and distributes energy. Just as a smart thermostat learns to regulate your home’s temperature efficiently, MOTS-c appears to help cells adapt their energy usage based on current needs, potentially improving everything from metabolism to stress response.

Discovered relatively recently in the world of peptide research, MOTS-c represents an exciting frontier in understanding how our mitochondria communicate with the rest of our cells. This 16-amino acid peptide has shown remarkable promise in laboratory studies for its ability to influence metabolic pathways, cellular aging, and overall energy homeostasis.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C101H152N28O22S2

Weight: 2174.6 g/mol

CAS: 1627580-64-6

Sequence: 16 amino acids

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

Stability: Stable when properly stored

How It Works

MOTS-c operates like a master switch for cellular metabolism, activating multiple pathways that help cells use energy more efficiently. When released from mitochondria, this peptide travels throughout the cell and even into the bloodstream, where it can influence metabolism on a whole-body level.

Primary Mechanisms

AMPK Pathway Activation

Acts as your cells’ fuel gauge sensor. When AMPK is activated, cells become more efficient at burning fat for energy and maintaining healthy insulin sensitivity.

Metabolic Regulation

Influences glucose uptake from the bloodstream and optimizes cellular energy utilization across all systems.

Secondary Effects

Gene Expression Modulation

Influences gene expression related to metabolism and aging, potentially helping cells maintain their youthful function longer.

Multi-Level Approach

This comprehensive mechanism makes MOTS-c a fascinating subject for metabolic and longevity research.

Research Findings

Laboratory investigations have revealed multiple areas where MOTS-c demonstrates significant research potential.

Metabolic Health Enhancement

Laboratory studies have shown significant improvements in metabolic parameters.

Exercise-mimetic properties demonstrated in 2024 studies
Improves insulin sensitivity through AMPK activation
Reduces cognitive decline in aging models (2023)
Enhances mitochondrial biogenesis and oxidative capacity
Increases glucose uptake independent of insulin
Better blood sugar control in high-fat diet models
Reduced fat accumulation in research subjects
Potential applications in metabolic disorder research

Cellular Energy Optimization

Research indicates enhanced mitochondrial function and energy production.

Promotes burning of fatty acids for energy
Increased ATP production in treated cells
Improved endurance in animal models
More efficient energy utilization overall

Neuroprotective Properties

Emerging research suggests protective effects on brain cells.

Protection from oxidative stress
Reduced age-related neuronal damage
Improved cognitive function in models
Decreased neuroinflammation markers

Longevity and Healthy Aging

Studies show potential for extending healthspan in research models.

Extended lifespan in certain models
Activation of longevity-associated genes
Protection from cellular stress
Natural decline with age makes it a key target

Cardiovascular Support

Preliminary studies suggest cardiovascular protective properties.

Protection of heart tissue from damage
Reduced inflammation in blood vessels
Better heart muscle performance
Improved cardiovascular function markers

Potential Side Effects in Research

Current research has reported remarkably few adverse effects associated with MOTS-c in laboratory settings. However, as with any research compound, careful monitoring is essential.

Metabolic Monitoring

Potential changes in blood glucose levels requiring monitoring in diabetic research models

Administration Effects

Possible mild injection site reactions in animal studies

Long-term Considerations

Theoretical concerns about long-term metabolic adaptations that require further investigation

Drug Interactions

Limited data on interactions with other compounds or medications

Most research has been conducted in cell cultures and animal models, with human studies still in early stages. Researchers should maintain detailed records of any observed effects during their investigations.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

✓ THIRD-PARTY LAB TESTED

Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.547%
Purity
47CBF
Batch
January 2026
Date
View Certificate →
Weight 0.08 lbs
Dimensions 0.87 × 1.18 × 0.87 in
Size

5mg, 10mg, 40mg
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