GHRP-6

GHRP-6

$35.00

GHRP-6 (Growth Hormone Releasing Peptide-6) is a pioneering synthetic hexapeptide that was the first GHRP discovered to effectively stimulate growth hormone release. This groundbreaking compound opened new avenues in endocrine research by demonstrating that synthetic peptides could mimic ghrelin’s action on the pituitary gland. Beyond its GH-releasing properties, GHRP-6 has revealed fascinating neuroprotective and anti-inflammatory effects that continue to intrigue researchers worldwide.

Each vial contains pure, lyophilized powder for reconstitution. This product is exclusively for laboratory research and not for human or animal use.

Overview

GHRP-6 holds a special place in peptide research history as the original synthetic ghrelin mimetic. Discovered in the 1980s, this hexapeptide demonstrated that small synthetic molecules could activate the growth hormone secretagogue receptor, fundamentally changing our understanding of GH regulation. What makes GHRP-6 particularly intriguing is its diverse biological activities – while primarily known for stimulating growth hormone release, research has uncovered additional protective effects on neurons, heart tissue, and the immune system, making it a versatile tool for multiple research applications.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C46H56N12O6

Weight: 873.01 g/mol

CAS: 87616-84-0

Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Readily dissolves in water

Stability: Stable when properly stored

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

How It Works

GHRP-6 activates multiple pathways that extend beyond simple GH release:

Primary Mechanisms

GHS-R Activation

Binds to ghrelin receptors with high affinity, triggering GH release from somatotrophs

Hypothalamic Signaling

Stimulates GHRH neurons while inhibiting somatostatin release

PKC Activation

Activates protein kinase C pathways for sustained cellular responses

cAMP Modulation

Enhances cyclic AMP accumulation in pituitary cells

Unique Properties

Neuroprotection

Demonstrates protective effects on neurons independent of GH

Anti-inflammatory Action

Reduces inflammatory markers through multiple pathways

Cardioprotection

Shows protective effects on cardiac tissue in research models

Research Findings

GHRP-6’s research applications span multiple physiological systems:

Endocrine Effects

Classic growth hormone secretagogue actions:

Potent GH release within 15-30 minutes of administration
Dose-dependent response with ceiling effect
Increased IGF-1 production following GH elevation
Enhanced pulsatile GH secretion patterns

Neuroprotective Research

Emerging evidence for brain protection:

Protection against excitotoxic injury
Reduced neuroinflammation in research models
Potential benefits in Parkinson’s disease models
Memory and learning enhancement studies

Tissue Protection

Protective effects across multiple organs:

Cardioprotection in ischemia-reperfusion models
Liver protection against various insults
Kidney preservation in injury models
Accelerated wound healing observations

Metabolic Studies

Complex metabolic effects observed:

Powerful appetite stimulation via ghrelin pathways
Altered glucose metabolism and insulin sensitivity
Changes in lipid profiles and fat distribution
Enhanced muscle protein synthesis

Potential Side Effects in Research

GHRP-6 shows a distinct side effect profile in research settings:

Intense Hunger

Very strong appetite stimulation, more pronounced than GHRP-2

Cortisol/Prolactin

Moderate increases in cortisol and prolactin levels

Gastric Effects

Increased gastric motility and digestive activity

Injection Site

Mild irritation or redness at administration sites

The pronounced appetite stimulation of GHRP-6 makes it particularly useful for research into hunger signaling.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

Third-Party Lab Tested

View our independent laboratory test certificate showing purity and composition analysis.


📋 View Test Certificate →

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5mg
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