GHRP-2

Price range: $35.00 through $50.00

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide that potently stimulates growth hormone secretion from the pituitary gland. As one of the first-generation growth hormone secretagogues, GHRP-2 has become a cornerstone in research exploring the endocrine system, metabolism, and tissue regeneration. Its ability to trigger robust, dose-dependent GH release makes it an invaluable tool for studying growth hormone physiology and potential therapeutic applications.

Each vial contains pure, lyophilized powder for reconstitution. This product is exclusively for laboratory research and not for human or animal use.

Overview

GHRP-2 represents a significant advancement in growth hormone research. This synthetic peptide, also known as pralmorelin, was among the first compounds discovered to stimulate GH release through the ghrelin receptor pathway. What makes GHRP-2 particularly valuable for research is its potency – it can elicit growth hormone release that rivals or exceeds the body’s natural GHRH (growth hormone releasing hormone), providing researchers with a powerful tool to study the complexities of the growth hormone axis.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C45H55N9O6

Weight: 817.99 g/mol

CAS: 158861-67-7

Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Readily dissolves in water

Stability: Stable when lyophilized

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

How It Works

GHRP-2 operates through sophisticated mechanisms that amplify the body’s natural growth hormone release:

Primary Mechanisms

Ghrelin Receptor Activation

Binds to growth hormone secretagogue receptors (GHS-R) in the pituitary and hypothalamus

Dual Action

Stimulates GH release while simultaneously reducing somatostatin (the GH inhibiting hormone)

Calcium Channel Modulation

Increases intracellular calcium in somatotrophs, triggering GH vesicle release

GHRH Synergy

Works synergistically with natural GHRH for amplified GH release

Secondary Effects

ACTH/Cortisol Stimulation

Mild elevation of ACTH and cortisol levels

Prolactin Release

Slight increase in prolactin secretion

Appetite Modulation

Influences hunger signaling through ghrelin pathways

Research Findings

GHRP-2 has been extensively studied across multiple research domains:

Growth Hormone Dynamics

Studies demonstrate GHRP-2’s powerful GH-releasing effects:

Dose-dependent GH release with peak levels at 30-60 minutes
Can increase GH levels 7-15 fold in research models
Maintains effectiveness with repeated administration
Synergistic effects when combined with GHRH

Metabolic Research

GHRP-2 influences various metabolic parameters:

Enhanced protein synthesis and nitrogen retention
Improved insulin sensitivity in some models
Altered lipid metabolism and body composition
Increased IGF-1 production

Cardiovascular Studies

Emerging research on cardiac effects:

Potential cardioprotective properties
Improved cardiac output in certain models
May influence vascular function
Research into post-MI recovery applications

Anti-Aging Research

Studies exploring age-related applications:

Restoration of GH levels in aging models
Potential effects on muscle mass preservation
Bone density maintenance studies
Cognitive function research

Potential Side Effects in Research

GHRP-2 generally shows good tolerability in research settings, with some notable observations:

Increased Hunger

Strong appetite stimulation due to ghrelin receptor activation

Cortisol Elevation

Mild to moderate increases in cortisol levels

Water Retention

Temporary fluid retention in some research models

Injection Site Reactions

Occasional irritation at administration sites

These effects are generally dose-dependent and transient in research applications.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

✓ THIRD-PARTY LAB TESTED

Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.256%
Purity
51HBE
Batch
August 2025
Date
View Certificate →
Weight 0.08 lbs
Dimensions 0.87 × 1.18 × 0.87 in
Size

10mg, 5mg

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