GHK-Cu

$45.00

GHK-Cu is a naturally occurring copper peptide that acts as a master regulator of tissue repair and regeneration. This tripeptide complex combines the amino acids glycine, histidine, and lysine with copper to create a powerful research tool for studying skin health, wound healing, and anti-aging processes. Found naturally in human plasma, saliva, and urine, GHK-Cu levels decline with age, making it a fascinating subject for longevity research.

Each vial contains pure, lyophilized blue powder for reconstitution. This product is exclusively for laboratory research and not for human or animal use.

Overview

GHK-Cu represents one of nature’s most elegant solutions for tissue repair and regeneration. This small but mighty copper peptide was first discovered in human plasma and has since been found to orchestrate a symphony of healing processes throughout the body. What makes GHK-Cu particularly intriguing is its ability to “reset” gene expression patterns to a more youthful state – it can actually influence over 4,000 human genes, many of which are involved in tissue repair, inflammation control, and antioxidant defense.

This product is strictly for research purposes only. It is not approved for human or animal use and should only be handled by qualified researchers in appropriate laboratory settings.

Key Characteristics

MOLECULAR PROFILE

Formula: C14H21CuN6O4

Weight: 404.9 g/mol

CAS: 89030-95-5

Structure: Gly-His-Lys (with bound copper)

PHYSICAL PROPERTIES

Form: Blue crystalline powder (the blue color comes from the copper)

Solubility: Highly water-soluble

Natural Occurrence: Found in human plasma, saliva, and urine

Storage: Keep refrigerated 36‑46 °F (2‑8 °C), protect from light

How It Works

GHK-Cu operates as a biological conductor, orchestrating multiple repair and regeneration processes:

Primary Mechanisms

Gene Expression Modulation

Resets genetic patterns to promote healing and reduce inflammation

Collagen Production

Dramatically increases collagen synthesis while improving its organization

Copper Delivery

Provides bioavailable copper essential for numerous enzymatic processes

Growth Factor Activation

Stimulates production of various growth factors crucial for tissue repair

Antioxidant Enhancement

Boosts the body’s natural antioxidant systems

Cellular Effects

Stem Cell Activation

Attracts and activates stem cells to areas needing repair

Blood Vessel Formation

Promotes angiogenesis for improved tissue nutrition

Debris Removal

Activates systems that clear damaged proteins and cellular debris

Barrier Function

Strengthens skin barrier and improves moisture retention

Research Findings

The research on GHK-Cu spans decades and reveals remarkable versatility:

Skin Rejuvenation and Anti-Aging

Studies consistently show GHK-Cu’s ability to reverse signs of aging in skin.

Modulates expression of 4,000+ human genes
Upregulates 47 DNA repair genes
31.2% of genes show ≥50% expression change
59% of affected genes upregulated, 41% suppressed
Resets gene expression to younger state

Collagen & ECM Enhancement

Comprehensive effects on extracellular matrix components in research models.

Increases collagen IV synthesis by 25.4-fold with hyaluronic acid (2023)
Stimulates collagen I, III, and elastin in dermal fibroblasts
Upregulates decorin and glycosaminoglycan production
Modulates matrix metalloproteinases and TIMPs
Restores ECM integrity in aged and photodamaged skin

Wound Healing Acceleration

Research demonstrates exceptional wound healing properties in laboratory studies.

Accelerates wound closure in diabetic and ischemic models
Reduces TNF-β and metalloproteinases 2 and 9
Stimulates VEGF and fibroblast growth factor production
Increases keratinocyte proliferation and migration
Improved healing of chronic, non-healing wounds

Anti-Inflammatory Effects

GHK-Cu demonstrates powerful anti-inflammatory properties in research settings.

Reduces TNF-α induced IL-6 secretion in fibroblasts
Suppresses NFκB signaling pathway activation
Decreases pro-inflammatory cytokine expression
Modulates oxidative stress markers
Alternative to corticosteroids in research models

Hair Growth Stimulation

Emerging research shows promise for hair regrowth applications.

Increased hair follicle size in studies
Extended growth phase of hair cycle
Improved scalp circulation markers
Potential reversal of miniaturization in androgenic alopecia

Systemic Anti-Aging Effects

Research reveals broad systemic benefits across multiple physiological markers.

Endogenous levels: 200 ng/ml (age 20) to 80 ng/ml (age 60)
Reduced appearance of fine lines and wrinkles
Improved skin clarity and tone measurements
Enhanced production of elastin and collagen
Tightening of loose skin in research models

Potential Side Effects in Research

GHK-Cu shows an excellent safety profile in research settings:

Skin Application

Occasional mild irritation or redness

Allergic Reactions

Rare hypersensitivity responses

Copper Sensitivity

Theoretical concern in copper-sensitive subjects

Systemic Effects

No significant adverse effects reported in studies

The natural occurrence of GHK-Cu in the human body contributes to its excellent tolerability profile.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

Weight N/A
Dimensions N/A
Size

50mg

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