hGH Fragment 176-191

$99.99

GH Fragment 176-191 is a powerful research peptide that isolates the fat-burning region of human growth hormone. This 16-amino acid sequence represents the exact portion of HGH responsible for lipolysis, offering researchers a targeted approach to studying fat metabolism without growth-related effects.

As the precursor to AOD9604, this fragment demonstrates remarkable specificity for adipose tissue. Each vial contains pure, lyophilized powder for reconstitution. This product is exclusively for laboratory research and not for human or animal use.

Overview

GH Fragment 176-191 represents a masterpiece of molecular precision. By isolating just the final 16 amino acids from the 191-amino acid chain of human growth hormone, researchers discovered the specific sequence responsible for fat mobilization. It’s like finding the exact key that unlocks the body’s fat-burning machinery while leaving all other doors closed.

This peptide fragment has revolutionized metabolic research by demonstrating that HGH’s various functions can be separated and studied independently. Fragment 176-191 provides all the lipolytic benefits of growth hormone without any of its effects on growth, insulin resistance, or IGF-1 production – making it an invaluable tool for targeted research.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Origin: HGH amino acids 176-191

Size: 16 amino acids

Percentage of HGH: Less than 10%

Structure: Contains disulfide bond

PHYSICAL PROPERTIES

Form: White lyophilized powder

Solubility: Water-soluble

Stability: Stable with proper storage

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

How It Works

Fragment 176-191 employs multiple mechanisms to target fat metabolism:

Primary Mechanisms

Lipolysis Activation

Stimulates hormone-sensitive lipase to break down stored fat

Adipocyte Vascular Disruption

Blocks blood vessel formation to fat cells, limiting their growth

Beta-3 Receptor Interaction

Enhances thermogenesis and energy expenditure in adipose tissue

Energy Expenditure Enhancement

Increases metabolic rate specifically in fat tissue

Selective Benefits

No IGF-1 Impact

Completely avoids growth factor elevation

Insulin Neutral

No effect on glucose metabolism or insulin sensitivity

Targeted Fat Loss

Affects only adipose tissue without muscle catabolism

Research Findings

Laboratory studies have revealed Fragment 176-191’s impressive capabilities:

Weight Loss Studies

Animal research demonstrates significant results:

Nearly 50% reduction in weight gain in obese models
Selective reduction of adipose tissue
Preservation of lean muscle mass
Enhanced fat oxidation markers
Sustained effects after treatment cessation

Metabolic Benefits

Studies show targeted metabolic improvements:

Increased energy expenditure in fat cells
Enhanced mitochondrial function
No impact on thyroid hormones
Maintained metabolic rate
Improved fat-to-muscle ratio

Cartilage Regeneration

Emerging research in joint health:

Enhanced effects with hyaluronic acid combination
Potential cartilage protective properties
Reduced inflammatory markers in joints
Improved mobility in arthritis models
Synergistic effects with other peptides

Cancer Research Applications

Laboratory studies indicate potential for:

Enhanced doxorubicin efficacy in breast cancer cells
Potential anti-proliferative effects
Adipocyte-cancer cell interaction studies
Metabolic reprogramming research
Combination therapy investigations

Potential Side Effects in Research

Fragment 176-191 shows a favorable safety profile compared to full HGH:

Injection Site

Mild local reactions possible

Fatigue

Temporary tiredness in some subjects

Headaches

Occasional mild headaches reported

No Growth Effects

No carpal tunnel or joint pain

No Insulin Issues

No insulin resistance development

No Water Retention

Unlike full HGH treatment

The selective action eliminates most side effects associated with full growth hormone.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

Weight N/A
Size

5mg

SKU: OATH-GH-FRAGMENT-176-191 Category: Tags: , ,
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