Epithalon

Price range: $60.00 through $190.00

Epithalon is a remarkable anti-aging research peptide that works at the cellular level to promote longevity and vitality. This synthetic tetrapeptide mirrors a natural substance produced by the pineal gland, helping to regulate biological rhythms and protect cells from age-related damage. Known for its potential to influence telomere length and cellular regeneration, Epithalon offers researchers a unique tool for studying the aging process. Each vial contains pure, lyophilized powder for reconstitution.

This product is exclusively for laboratory research and not for human or animal use. Epithalon should only be handled by qualified researchers in appropriate laboratory settings.

Overview

Epithalon, also known as Epitalon or Epithalone, is like a cellular fountain of youth in peptide form. Originally discovered in the pineal gland, this four-amino acid chain has captured the attention of longevity researchers worldwide. What makes Epithalon particularly fascinating is its potential to influence the very mechanisms of aging at the chromosomal level, including the maintenance of telomeres – the protective caps on our DNA that shorten as we age.

This product is strictly for research purposes only. Not approved for human or animal use.

Key Characteristics

MOLECULAR PROFILE

Formula: C14H22N4O9

Weight: 390.34 g/mol

CAS: 307297-39-8

Structure: Ala-Glu-Asp-Gly

PHYSICAL PROPERTIES

Form: White lyophilized powder

Solubility: Readily dissolves in water

Origin: Synthetic version of epithalamin

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

How It Works

Epithalon operates through several interconnected mechanisms that target aging at its roots:

Primary Mechanisms

Telomerase Activation

May stimulate telomerase enzyme, potentially maintaining or lengthening telomeres

Melatonin Regulation

Helps normalize melatonin production and circadian rhythms

Antioxidant Enhancement

Reduces oxidative stress and protects cells from damage

Cellular Protection

DNA Preservation

Helps maintain genetic integrity

Mitochondrial Support

Enhances cellular energy production

Neuroendocrine Balance

Helps regulate hormonal systems

Research Findings

Decades of research have revealed Epithalon’s remarkable potential across multiple physiological systems.

Anti-Aging Effects

Studies demonstrate significant anti-aging properties:

Extended lifespan in research models
Improved markers of biological age
Enhanced cellular regeneration
Reduced age-related deterioration
Maintained youthful gene expression patterns

Sleep and Circadian Rhythm

Research shows profound effects on sleep quality:

Normalized melatonin production
Improved sleep architecture
Better circadian rhythm synchronization
Enhanced deep sleep phases
Reduced sleep disturbances with aging

Neuroprotective Properties

Studies reveal brain-protective effects:

Improved cognitive function in aging models
Protection against neurodegenerative processes
Enhanced memory and learning
Reduced brain inflammation
Maintained neural plasticity

Cardiovascular Benefits

Research indicates heart and vascular protection:

Improved cardiovascular function
Better blood pressure regulation
Enhanced vascular elasticity
Reduced oxidative stress in blood vessels
Protection against age-related cardiac changes

Immune System Support

Studies show immunomodulatory effects:

Restoration of T-cell function
Improved immune response in aging
Better resistance to infections
Balanced inflammatory responses
Enhanced immune surveillance

Vision and Eye Health

Research suggests benefits for ocular health:

Protection against age-related vision decline
Improved retinal function
Reduced cataract formation
Better intraocular pressure regulation

Potential Side Effects in Research

Epithalon demonstrates an exceptional safety profile. This outstanding safety profile makes Epithalon particularly valuable for longevity research.

General Tolerance

Extremely well-tolerated across studies

No Toxicity

No toxic effects observed even at high doses

Minimal Side Effects

Rare reports of mild injection site reactions

No Drug Interactions

No significant interactions reported

Long-term Safety

Studies show safety with extended use

This outstanding safety profile makes Epithalon particularly valuable for longevity research.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

References

  1. Khavinson VK, et al. “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.” Bull Exp Biol Med. 2003.
  2. Anisimov VN, et al. “Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence.” Biogerontology. 2003.
  3. Phelan J, et al. “Improving biological age, telomere length, and cognition: A case report.” Restor Med. 2024.
  4. Korkushko OV, et al. “Normalizing effect of the pineal gland peptides on the daily melatonin rhythm.” Bull Exp Biol Med. 2004.
  5. Khavinson V, et al. “AEDG Peptide (Epitalon) Stimulates Gene Expression.” Molecules. 2020.
  6. Goncharova ND, et al. “Pineal peptides restore the age-related disturbances in hormonal functions.” Exp Gerontol. 2005.
  7. Khavinson VK, Morozov VG. “Peptides of pineal gland and thymus prolong human life.” Neuro Endocrinol Lett. 2003.
  8. Anisimov VN, Khavinson VK. “Peptide bioregulation of aging: results and prospects.” Biogerontology. 2010.
  9. Khavinson V, et al. “Neuroprotective Effect of EDR Peptide.” Pharmaceuticals. 2021.
  10. Kozina LS, et al. “Investigation of the correction effect of livagen peptide.” Bull Exp Biol Med. 2008.
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10mg, 50mg

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