CJC-1295/Ipamorelin

CJC-1295/Ipamorelin

$135.00

This powerful research blend combines CJC-1295 without DAC (5mg) and Ipamorelin (5mg) in a perfectly balanced 1:1 ratio. These two growth hormone-releasing peptides work through complementary mechanisms – CJC-1295 extends the natural release of growth hormone while Ipamorelin amplifies the pulse strength. Together, they create a synergistic effect that researchers report can triple growth hormone levels compared to either peptide alone, making this blend invaluable for studying pituitary function, metabolic regulation, and tissue regeneration.

Each vial contains pure, lyophilized powder blend for reconstitution. This product is exclusively for laboratory research and not for human or animal use.

Overview

This blend represents one of the most synergistic combinations in growth hormone research. Think of it as a perfectly choreographed duet where CJC-1295 without DAC (also known as Mod GRF 1-29) acts as the conductor, extending the duration of each growth hormone performance, while Ipamorelin serves as the virtuoso soloist, creating powerful crescendos of hormone release. Neither peptide overwhelms the body’s natural rhythms; instead, they enhance and optimize what nature intended.

What makes this combination particularly elegant is how each peptide addresses different aspects of growth hormone secretion. CJC-1295 without DAC works by preventing the breakdown of your body’s own growth hormone-releasing hormone, effectively keeping the signal to produce GH active for longer periods. Meanwhile, Ipamorelin selectively triggers the pituitary to release stronger pulses of growth hormone without affecting other hormones like cortisol or prolactin. The result? A more physiological pattern of GH release that researchers find produces 3-5 times more growth hormone than either peptide alone.

This product is strictly for research purposes only. Not approved for human or animal use.

Blend Composition

PEPTIDE COMPONENTS

CJC-1295 no DAC: 5mg (Modified GRF 1-29)

Ipamorelin: 5mg (Pentapeptide)

Total Peptide: 10mg

Ratio: 1:1 Equal blend

PHYSICAL PROPERTIES

Form: White lyophilized powder

Solubility: Readily dissolves in water

Stability: Enhanced compared to native GHRH

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

Synergistic Mechanisms

The combination creates a powerful synergy by addressing different aspects of growth hormone release:

CJC-1295 without DAC Actions

GHRH Analog Function

Modified version of GHRH (1-29) with enhanced stability

Extended Half-Life

30-minute half-life vs 7 minutes for native GHRH

Pulse Frequency

Increases the frequency of GH pulses

Resistance to Degradation

Four amino acid substitutions prevent enzymatic breakdown

Ipamorelin Actions

Ghrelin Receptor Agonist

Selective activation of GHS-R1a receptors

Pulse Amplitude

Increases the strength of each GH pulse

Selective Action

No effect on cortisol, prolactin, or ACTH

Rapid Onset

Fast-acting with 2-hour half-life

Combined Synergistic Effects

When combined, these peptides create enhanced growth hormone release through:

3-5x GH Increase: Significantly higher than either peptide alone

Natural Pulsatility: Maintains physiological GH release patterns

Extended Duration: Longer-lasting effects with rapid onset

Selective Action: GH-specific without affecting other hormones

Research Applications

This blend is particularly valuable for comprehensive growth hormone research:

Metabolic Function Studies

Research demonstrates significant metabolic improvements:

Enhanced fat metabolism and lipolysis
Improved insulin sensitivity markers
Better glucose utilization
Increased metabolic rate
Optimized nutrient partitioning

Body Composition Research

Studies show improvements in tissue quality:

Increased lean muscle mass development
Reduced body fat percentage
Enhanced muscle protein synthesis
Improved muscle-to-fat ratio
Better overall body recomposition

Recovery and Regeneration

Enhanced tissue repair and recovery processes:

Accelerated post-exercise recovery
Improved connective tissue repair
Enhanced bone mineral density
Faster wound healing
Reduced recovery time between training

Sleep and Well-being

Research on quality of life parameters:

Improved deep sleep quality
Enhanced REM sleep patterns
Better mood and cognitive function
Increased energy levels
Improved stress resilience

Age-Related Research

Studies on aging and longevity markers:

Improved skin elasticity and thickness
Enhanced collagen production
Better cellular regeneration
Reduced age-related muscle loss
Improved mitochondrial function

Cardiovascular Health

Heart and vascular system benefits:

Improved cardiac output
Better endothelial function
Enhanced lipid profiles
Reduced inflammatory markers
Improved vascular flexibility

Research Advantages

Why this blend is preferred for growth hormone research:

Superior Efficacy

3-5 fold increase in GH release compared to single peptides

Physiological Pattern

Maintains natural pulsatile GH secretion

No Desensitization

Sustained effectiveness with continued research use

Selective Action

GH-specific without affecting cortisol or prolactin

Complementary Kinetics

Fast onset from Ipamorelin, extended duration from CJC-1295

Research Flexibility

1:1 ratio allows easy dosing calculations

This blend represents the gold standard for growth hormone secretagogue research.

IMPORTANT: This product is exclusively for laboratory research purposes and is not approved for human or veterinary use.

References

  1. Ishida J, et al. “Growth hormone secretagogues: history, mechanism of action, and clinical development.” JCSM Rapid Communications. 2020.
  2. Deepankar K, et al. “Beyond the androgen receptor: the role of growth hormone secretagogues in body composition.” Transl Androl Urol. 2020.
  3. Walpurgis K, et al. “An immuno-PCR screen for detection of CJC-1295 and GH-releasing hormone analogs.” Drug Test Anal. 2019.
  4. Sackmann-Sala L, et al. “Activation of the GH/IGF-1 axis by CJC-1295.” Growth Horm IGF Res. 2009.
  5. Veldhuis JD, et al. “Synergistic release of growth hormone by GHRH and GHRP.” Pituitary. 2009.
  6. Ionescu M, Frohman LA. “Pulsatile secretion of growth hormone persists during continuous stimulation.” J Clin Endocrinol Metab. 2006.
  7. Teichman SL, et al. “Prolonged stimulation of GH and IGF-I secretion by CJC-1295.” J Clin Endocrinol Metab. 2006.
  8. Alba M, et al. “Once-daily administration of CJC-1295.” J Clin Endocrinol Metab. 2005.
  9. Beck DE, et al. “Comparison of ipamorelin and GHRP-6 effects.” Peptides. 2002.
  10. Jimenez-Reina L, et al. “Influence of ipamorelin on the GH/IGF-1 axis.” Growth Horm IGF Res. 2001.
  11. Gobburu JV, et al. “Pharmacokinetics/dynamics of ipamorelin.” J Clin Pharmacol. 1999.
  12. Raun K, et al. “Ipamorelin, the first selective growth hormone secretagogue.” Eur J Endocrinol. 1998.

Third-Party Lab Tested

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10mg, 5mg
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