GLP-1 receptor agonists have transformed metabolic research over the past decade, offering unprecedented insights into glucose regulation, satiety mechanisms, and body weight control. These peptides mimic the action of glucagon-like peptide-1, an incretin hormone that plays a central role in postprandial glucose metabolism. While research continues to expand our understanding of these compounds, it’s equally …

Understanding the FDA’s Position on BPC-157 The regulatory status of BPC-157 changed dramatically in February 2024 when the FDA issued guidance explicitly prohibiting compounded drugs containing this peptide. While the term “blacklisted” isn’t official FDA terminology, the agency’s position is clear: BPC-157 cannot legally be prescribed, compounded, or marketed for human use in the United …

GLP-1 receptor agonists like GLP1-S have gained attention in metabolic research, but their potential to interact with oral medications raises important questions for laboratory studies. Understanding these interactions is critical for researchers designing comprehensive protocols that account for pharmacokinetic and pharmacodynamic variables. The gastroparetic effects of GLP-1 receptor agonists can significantly alter the absorption profile …

BPC-157 is not FDA approved for human use. This synthetic peptide, derived from a protective protein in gastric juice, remains classified as a research compound. While numerous preclinical studies have documented its potential regenerative properties, BPC-157 has not undergone the rigorous laboratory studie(s) process required for FDA approval as a pharmaceutical drug. The regulatory landscape …

CJC-1295 is one of the most discussed growth hormone-releasing hormones (GHRH) in peptide research. However, there’s significant confusion about two distinct versions: CJC-1295 with DAC and CJC-1295 without DAC (also called Modified GRF 1-29). While they share similar names, these peptides function quite differently in research applications. The primary distinction lies in their half-life and …

Peptides have emerged as powerful tools in the research of cellular aging and dermal health. These short chains of amino acids act as signaling molecules, influencing everything from collagen synthesis to cellular repair mechanisms. Unlike topical cosmetics that work at the surface level, research peptides interact with cellular pathways to address aging at its source. …

In June 2022, the FDA issued a warning letter that fundamentally changed the landscape for BPC-157, a synthetic peptide that had gained significant popularity in research and wellness communities. The regulatory action didn’t technically “ban” BPC-157 outright, but it effectively prohibited compounding pharmacies from producing it for human use—a distinction that matters when understanding what …